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. 2018 Oct 19;23(10):2696. doi: 10.3390/molecules23102696

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Michaelis-Menten plots for zidovudine (ZDV) glucuronidation catalyzed by (A) human liver microsomes (HLM) and (B) rat liver microsomes (RLM) with and without 1% (w/v) of bovine serum abumin (BSA). Each point represents the mean of zidovudine glucuronides (ZDVG) formation rate ± standard deviation (SD) for triplicates (n = 3).