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. 2018 Sep 29;23(10):2498. doi: 10.3390/molecules23102498

Table 1.

The central composite design, coded and actual levels of three independent variables, actual and predicted values of total phenolic content.

Run X1 (Ethanol Concentration, %) X2 (Solvent/Material Ratio, mL/g) X3 (Temperature, °C) Y (TPC Value, mg GAE/g DW)
Actual Predicted
1 20 (−1) 40 (1) 40 (−1) 28.71 27.70
2 40 (1) 40 (1) 60 (1) 30.32 30.32
3 30 (0) 30 (0) 50 (0) 39.30 38.68
4 30 (0) 46.82 (1.68) 50 (0) 30.33 30.50
5 40 (1) 20 (−1) 60 (1) 28.11 29.60
6 20 (−1) 20 (-1) 60 (1) 26.93 27.47
7 30 (0) 30 (0) 50 (0) 39.42 38.68
8 40 (1) 20 (−1) 40 (−1) 23.11 22.42
9 30 (0) 30 (0) 66.82 (1.68) 32.63 30.96
10 30 (0) 30 (0) 50 (0) 38.17 38.68
11 20 (−1) 40 (1) 60 (1) 28.11 29.28
12 13.18 (−1.68) 30 (0) 50 (0) 27.72 27.25
13 40 (1) 40 (1) 40 (−1) 29.75 29.69
14 30 (0) 30 (0) 50 (0) 38.65 38.68
15 30 (0) 30 (0) 33.18 (−1.68) 22.61 23.60
16 20 (−1) 20 (−1) 40 (−1) 18.87 19.35
17 30 (0) 30 (0) 50 (0) 37.51 38.68
18 30 (0) 13.18 (−1.68) 50 (0) 23.72 22.87
19 46.82 (1.68) 30 (0) 50 (0) 30.91 30.70
20 30 (0) 30 (0) 50 (0) 38.90 38.68