Table 6.

The predicted inhibition constants Ki (nM) for the tested compounds-Als complexes.

Compound	Als1	Als2	Als3	Als4	Als5	Als6	Als7	Als9
4a	6.07	84.42	18.48	142.46	5.58	4.95	25.04	28.18
4b	4.18	54.43	11.92	81.62	4.33	3.25	8.36	15.61
4c	6.83	90.32	25.04	70.12	2.74	2.94	10.07	18.48
4d	7.95	63.36	40.86	140.07	2.52	2.94	11.52	38.19
5a	3.30	35.70	36.92	88.81	4.79	6.07	40.17	49.19
5b	2.13	80.25	13.41	78.91	2.52	2.40	8.79	19.12
5c	3.66	105.13	16.99	68.94	2.70	2.48	6.28	25.47
5d	1.65	42.98	11.92	63.36	3.60	2.17	1.74	18.80
6a	8.94	95.01	21.15	174.44	6.07	4.71	33.93	84.42
6b	10.77	63.36	21.15	78.91	2.65	6.49	11.52	68.94
6c	8.79	66.65	22.63	105.13	6.17	8.36	24.21	73.76
6d	22.63	171.52	99.94	244.48	8.79	7.43	47.56	186.62
7a	7.95	257.18	42.98	149.86	12.54	7.18	55.36	45.98
7b	3.09	163.05	28.18	68.94	3.91	3.14	30.67	35.10
7c	7.06	110.59	29.15	99.94	2.84	4.87	20.11	18.48
7d	8.79	165.83	193.03	124.46	8.22	5.21	5.77	163.05
Berberine	60.23	1299.95	881.73	1438.49	1702.98	522.52	1761.44	147.35