Table 2.
Resistance index (RI) values of phenolic-phospholipids.
| Compounds | Acyl Residue | ||
|---|---|---|---|
| sn-1 | sn-2 | RI | |
| 1a (ANISA) | - | - | - |
| 3a | ANISA | ANISA | - |
| 5a | PA | ANISA | 1.11 |
| 7a | ANISA | - | 1.61 |
| 8a | ANISA | PA | 0.99 |
| 1b (VA) | - | - | - |
| 3b | VA | VA | 0.42 |
| 5b | PA | VA | 1.02 |
| 7b | VA | - | 2.86 |
| 8b | VA | PA | 1.04 |
| DOX | - | - | 55.81 |
DOX—doxorubicin. RI was calculated according to the formula RI = (IC50 estimated against resistant cell line) / (IC50 estimated against non-resistant cell line); values range: 0 < RI < 2—indicate that the tested compound is able to overcome drug resistance; 2 < RI < 10—defines the moderate ability of the compound to overcome drug resistance; RI > 10—defines no influence on the drug resistance phenomenon.