Table 1.

In vitro antimycobacterial, antitrichomonas, and cytotoxicity activities of cinnamic acid-benzoxaborole hybrids.

Compound	IC50 (μM)	MIC99 (μM)	%Viability
	T. vaginalis	H37Rv	HeLa Cells
5a	15.3 ± 0.33	61.8	108.5 ± 5.35
5b	41.7 ± 0.23	107	87.0 ± 1.59
5c	10.2 ± 0.56	26.5	94.3 ± 28.8
5d	12.6 ± 0.28	10.7	89.9 ± 5.12
5e	11.7 ± 0.28	18.7	102.5 ± 2.34
5f	˃50	˃125	109.9 ± 0.84
5g	22.8 ± 1.02	40.7	131.5 ± 26.6
EM	-	-	3.195
ME	0.53	-	-
RE	-	0.003	-

EM = emetine, ME = metronidazole, RE = rifampicin.