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. 2018 Oct 8;23(10):2568. doi: 10.3390/molecules23102568

Figure 1.

Figure 1

MeOH extract of the culture broth of the entomopathogenic fungus B. bassiana (BB) inhibited TGF-β1-induced myofibroblast differentiation in alveolar epithelial A549 cells. A549 cells were treated with TGF-β1 (2 ng/mL) and MeOH extract for 48 h. (A) Cytotoxicity of MeOH extract in A549 cells was measured by WST-1 assay at 48 h. (B) Expression of collagen (Col1A1) and E-cadherin was analyzed by qPCR-analysis. (C) The protein expression of E-cadherin was analyzed by western blot assay. All the assays were performed in triplicate, and the data are shown as the mean value ± S.D. Values that are significantly different from the control are indicated by ### p < 0.001, significantly different from the TGF-β1-treatment group, ** p < 0.01, or *** p < 0.001.