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The predicted binding modes of dodeca-2E,4E,8Z,10E-tetraenoic acid 2-methylbutylamide to the PPARγ LBD illustrated in a 2D-model (top) and 3D-model (bottom). The chemical interaction pattern is the same for dodeca-2E,4E,8Z,10Z-tetraenoic acid 2-methylbutylamide. Binding modes to the LBD in the 2D-model are color-coded: red dashed arrow = hydrogen bond; blue line = hydrophobic interactions.
