Table 3.
Variable | GARFIELD‐AF vs HAS‐BLED | ||||||||
---|---|---|---|---|---|---|---|---|---|
IDI | 95% CI | P Value | NRI | 95% CI | P Value | Median Improvement | 95% CI | P Value | |
Major bleeding | −0.002 | −0.007/0.003 | 0.318 | −0.042 | −0.189/0.087 | 0.448 | −0.002 | −0.010/0.005 | 0.308 |
Major/CRNM bleeding | 0.001 | −0.005/0.007 | 0.746 | 0.033 | −0.094/0.129 | 0.756 | 0.001 | −0.007/0.009 | 0.378 |
Any bleeding | −0.011 | −0.019/−0.005 | <0.001 | −0.087 | −0.131/−0.056 | <0.001 | −0.016 | −0.030/−0.001 | <0.001 |
CI indicates confidence interval; CRNM, clinically relevant nonmajor; GARFIELD‐AF, Global Anticoagulant in the Field–Atrial Fibrillation; HAS‐BLED, Hypertension, Abnormal renal and liver function, Stroke, Bleeding, Labile INRs, Elderly, Drugs or alcohol; IDI, integrated discrimination improvement; NRI, net reclassification improvement.