Table 1.
Baseline Characteristics by FGF‐23 Quartiles: The Multiethnic Study of Atherosclerosis 2000–2002
| Characteristic | Overall | FGF‐23 Quartiles | P Value | |||
|---|---|---|---|---|---|---|
| <31 pg/mL | 31–38 pg/mL | 38–46 pg/mL | >46 pg/mL | |||
| No. of participants | 6542 | 1636 | 1635 | 1636 | 1635 | |
| Age, y | 62±10 | 61±10 | 62±10 | 62±10 | 64±10 | <0.001 |
| Sex | ||||||
| Men | 3058 (47%) | 678 (41%) | 786 (48%) | 783 (48%) | 811 (50%) | <0.001 |
| Race/ethnicity | ||||||
| White, % | 2539 (39%) | 524 (32%) | 621 (38%) | 655 (40%) | 739 (45%) | <0.001 |
| Chinese, % | 795 (12%) | 192 (12%) | 214 (13%) | 194 (12%) | 195 (12%) | |
| Black, % | 1777 (27%) | 485 (30%) | 444 (27%) | 432 (26%) | 416 (25%) | |
| Hispanic, % | 1431 (22%) | 435 (27%) | 356 (22%) | 355 (22%) | 285 (17%) | |
| Diabetes mellitus | 809 (12%) | 203 (12%) | 201 (12%) | 175 (11%) | 230 (14%) | 0.03 |
| Current smoking | 843 (13%) | 274 (17%) | 218 (13%) | 199 (12%) | 152 (9%) | <0.001 |
| Education | ||||||
| High school or less (%) | 2314 (36%) | 527 (32%) | 606 (37%) | 576 (35%) | 605 (37%) | 0.004 |
| Some college (%) | 1174 (18%) | 333 (21%) | 324 (20%) | 289 (18%) | 228 (14%) | |
| College degree or more (%) | 3032 (46%) | 769 (47%) | 701 (43%) | 764 (47%) | 798 (49%) | |
| Body mass index (kg/m2) | 28±5.5 | 27.8±5.4 | 27.9±5.2 | 28.5±5.4 | 29±5.6 | <0.001 |
| SBP, mm Hg | 126±22 | 125±22 | 125±21 | 126±21 | 129±22 | <0.001 |
| HTN medication | 2400 (37%) | 511 (31%) | 534 (33%) | 583 (36%) | 772 (47%) | <0.001 |
| Estimated GFR, mL/min per 1.73 m2 | 81±18 | 87±17 | 83±20 | 81±17 | 75±18 | <0.001 |
| LV mass (g) (n=4827) | 120±29 | 116±28 | 120±29 | 121±30 | 124±31 | <0.001 |
Values are mean±SD. FGF‐23 indicates fibroblast growth factor‐23; GFR, glomerular filtration rate; HTN, hypertension; SBP, systolic blood pressure; Smoking, current and former vs never; LV mass, left ventricular mass.