Table 2.
Autopsy Findings of Cardiac Cases and Noncardiac Trauma Controls
| Characteristica | Cardiac Cases | Noncardiac Trauma Controls | P Value |
|---|---|---|---|
| Structure‐related measures | |||
| Heart weight, g (n=276; n=351) | 551±125 | 430±90 | <0.001 |
| Heart weight >450 g | 213 (77.2) | 114 (32.5) | <0.001 |
| Heart weight >550 g | 120 (43.5) | 32 (9.1) | <0.001 |
| LV wall thickness, cm (n=182; n=184) | 1.7±0.4 | 1.5±0.3 | <0.001 |
| LV wall thickness ≥1.2 cm | 175 (63.4) | 161 (45.9) | <0.001 |
| LV wall thickness ≥1.4 cm | 162 (58.7) | 127 (36.2) | <0.001 |
| Heart size abnormality noted (n=275; n=351) | 181 (65.8) | 74 (21.1) | <0.001 |
| Increased wall thickness noted (n=276; n=347) | 143 (51.8) | 50 (14.4) | <0.001 |
| Valve abnormalities noted (n=274; n=351) | 40 (14.6) | 12 (3.4) | <0.001 |
| CHD‐related measures | |||
| Coronary artery with ≥50% stenosis (n=214; n=103) | 202 (73.2) | 65 (18.5) | <0.001 |
| Coronary artery with ≥75% stenosis (n=214; n=103) | 165 (59.8) | 29 (8.3) | <0.001 |
| Multivessel disease, ≥50% stenosis (n=201; n=98) | 138 (50.0) | 22 (6.3) | <0.001 |
| Multivessel disease, ≥75% stenosis (n=201; n=98) | 89 (32.3) | 12 (3.4) | <0.001 |
| Coronary artery atherosclerosis noted (n=273; n=348) | 246 (90.1) | 131 (37.6) | <0.001 |
| Calcified plaque (n=276; n=349) | 113 (40.9) | 22 (6.3) | <0.001 |
| Plaque rupture (n=276; n=351) | 13 (4.7) | 0 (0.0) | <0.001 |
| Intracoronary thrombosis (n=276; n=349) | 45 (16.3) | 0 (0.0) | <0.001 |
| Evidence of prior MI (n=276; n=351) | 143 (51.8) | 23 (6.6) | <0.001 |
Values are reported as mean±SD or n (%). CHD indicates coronary heart disease; LV, left ventricular; MI, myocardial infarction.
a
Sample size indicates number of records with a numeric or yes/no value for cardiac cases and noncardiac trauma controls, respectively.