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. 2018 Sep 17;7(18):e009259. doi: 10.1161/JAHA.118.009259

Table 2.

Comparison of ICG Parameters Between Nonhypertensive, Stage 1 Hypertensive, and Stage 2 Hypertensive Subjects in the Study Sample

ACC/AHA Blood Pressure Group P Value
Nonhypertensive Stage 1 Hypertension Stage 2 Hypertension
Mean (95% CI) Mean (95% CI) Mean (95% CI)
Stroke volume, mL 80.4 (79–81.9) 83.2 (81.3–85) 77.2 (75.5–78.9) <0.0001a, b
Stroke index, mL/m2 47.4 (46.7–48) 47 (46.3–47.8) 43.7 (43–44.5) <0.0001a, b
Cardiac output, mL/min 5.01 (4.93–5.1) 5.22 (5.11–5.32) 4.99 (4.89–5.09) 0.0029b, c
Cardiac index, mL m2/min 2.91 (2.87–2.95) 2.91 (2.86–2.96) 2.76 (2.71–2.8) <0.0001a, b
SVR, dyn s/cm5 1132 (1112–1153) 1183 (1156–1209) 1389 (1358–1420) <0.0001a, b, c
SVR index, dyn s m2/cm5 1954 (1924–1985) 2124 (2083–2165) 2517 (2468–2566) <0.0001a, b, c
TAC, mL/mm Hg 2.03 (1.98–2.08) 1.88 (1.82–1.94) 1.37 (1.33–1.41) <0.0001a, b, c
TAC index, mL m2/mm Hg 1.175 (1.147–1.203) 1.049 (1.018–1.079) 0.757 (0.735–0.779) <0.0001a, b, c
Velocity index, 1/100 s 59.2 (57.8–60.6) 52 (50.5–53.5) 45.7 (44.4–47.1) <0.0001a, b, c
Acceleration index, 1/100 s2 104 (100.9–107) 88.8 (85.6–92) 77.4 (74.6–80.2) <0.0001a, b, c
Systolic time ratio 0.248 (0.244–0.252) 0.235 (0.231–0.24) 0.223 (0.218–0.227) <0.0001a, b, c
Pre‐ejection period, ms 85.7 (84.7–86.7) 84.9 (83.7–86.2) 80.8 (79.7–82) <0.0001a, b
LV ejection time, ms 338 (335–342) 353 (349–357) 355 (350–359) <0.0001a, c

Nonhypertensive: BP <13 080 mm Hg. Stage 1 hypertension: systolic BP 130 to 139 or diastolic BP 80 to 89 mm Hg; stage II hypertension: systolic BP ≥140 mm Hg or diastolic BP ≥90 mm Hg, or pharmacological treatment for hypertension. ACC indicates American College of Cardiology; AHA, American Heart Association; BP, blood pressure; CI, confidence interval; ICG, impedance cardiography; LV, left ventricular; SVR, systemic vascular resistance; TAC, total arterial compliance.

a

Post‐hoc pair‐wise comparison different between nonhypertensive and stage 2 hypertension.

b

Post‐hoc pair‐wise comparison different between stage 1 and 2 hypertension.

c

Post‐hoc pair‐wise comparison different between nonhypertensive and stage 1 hypertension.