Table 5.
L5_TPC:A | L5_TPC:B | L5_TPC:C | L5_UPC | t-test |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
(n = 60) | (n = 38) | (n = 33) | (n = 30) | TPC:A vs. TPC:B | TPC:A vs. TPC:C | TPC:A vs. UPC | TPC:B vs. TPC:C | TPC:B vs. UPC | TPC:C vs. UPC | ||
Soma | Perimeter(μm) | 83 ±2 | 85 ±2 | 71 ±4 | 68 ±3 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns |
Area(μm²) | 450 ±17 | 471±17 | 317±33 | 326 ±29 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Basal Dendrites | Max horizontal extend (μm) | 310 ±8 | 308 ±10 | 290 ±15 | 265 ±12 | ns | ns | < 0.05 | ns | < 0.05 | ns |
Max vertical extend (μm) | 252 ±8 | 268 ±12 | 247 ±12 | 274 ±20 | ns | ns | ns | ns | ns | ns | |
Den# | 7±0.2 | 7±0.3 | 6±0.3 | 6±0.3 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Length(μm) | 3882 ±184 | 4299±210 | 2642 ±203 | 3034±220 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Surface(μm²) | 10,645 ±661 | 11,713 ±747 | 5689 ±477 | 7454 ±735 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | |
Volume(μm³) | 2981 ±249 | 3285 ±285 | 1349±189 | 1889 ±264 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Tree length (μm) | 562 ±27 | 617 ±34 | 448 ±35 | 500 ±30 | ns | < 0.05 | ns | < 0.05 | < 0.05 | ns | |
Seg length (μm) | 65 ±2 | 59 ±2 | 72 ±4 | 69 ±6 | < 0.05 | < 0.05 | ns | < 0.05 | ns | ns | |
Seg surface (μm²) | 179 ±9 | 158 ±7 | 160 ±11 | 171 ±20 | ns | ns | ns | ns | ns | ns | |
Seg volume (μm³) | 52 ±5 | 44 ±3 | 39 ±5 | 44 ±7 | ns | ns | ns | ns | ns | ns | |
Seg# | 61 ±3 | 75 ±3 | 40 ±4 | 47 ±3 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Tortuosity | 1.28 ±0.01 | 1.25 ±0.01 | 1.28 ±0.01 | 1.28 ±0.01 | < 0.05 | ns | ns | ns | ns | ns | |
Max order | 6±0.2 | 6±0.2 | 5±0.3 | 5±0.2 | ns | < 0.05 | ns | < 0.05 | < 0.05 | ns | |
Mean order | 4±0.1 | 4±0.2 | 3±0.2 | 4±0.1 | < 0.05 | < 0.05 | ns | < 0.05 | < 0.05 | < 0.05 | |
Max angles | 55 ±1 | 57 ±1 | 53 ±1 | 57 ±2 | ns | ns | ns | ns | ns | ns | |
Planar angle | 41 ±1 | 43 ±1 | 40 ±1 | 43 ±1 | ns | ns | ns | ns | ns | ns | |
Local angle | 58 ±1 | 58 ±1 | 57 ±2 | 60 ±1 | ns | ns | ns | ns | ns | ns | |
Local spline angle | 51 ±1 | 51 ±1 | 50 ±2 | 53 ±1 | ns | ns | ns | ns | ns | ns | |
Apical Dendrites | Max horizontal extend (μm) | 356 ±10 | 350 ±13 | 252 ±11 | 216 ±10 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 |
Max vertical extend (μm) | 857 ±20 | 948 ±18 | 767 ±33 | 596 ±28 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | |
Length(μm) | 7280±267 | 8512 ±290 | 3522 ±246 | 2787 ±225 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | |
Surface(μm²) | 22,959±1117 | 26,835 ±1407 | 9177 ±884 | 7360 ±773 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Volume(μm³) | 8957±664 | 10,270 ±913 | 3151±549 | 2232 ±328 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Seg length (μm) | 69 ±2 | 66 ±3 | 77 ±3 | 75 ±5 | ns | < 0.05 | ns | < 0.05 | ns | ns | |
Seg surface (μm²) | 219 ±11 | 201 ±10 | 202±17 | 204 ±20 | ns | ns | ns | ns | ns | ns | |
Seg volume (μm³) | 87 ±8 | 73 ±5 | 66 ±11 | 63 ±9 | ns | ns | < 0.05 | ns | ns | ns | |
Seg# | 111 ±6 | 145 ±11 | 52 ±6 | 42 ±4 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Tortuosity | 1.28 ±0.01 | 1.26 ±0.01 | 1.27 ±0.01 | 1.27±0.01 | ns | ns | ns | ns | ns | ns | |
Max order | 21 ±1 | 23 ±1 | 15 ±1 | 14 ±1 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns | |
Max angles | 57 ±1 | 59 ±2 | 59 ±2 | 63 ±2 | ns | ns | < 0.05 | ns | ns | < 0.05 | |
Planar angle | 41 ±1 | 43 ±1 | 41 ±1 | 43 ±1 | ns | ns | ns | ns | ns | ns | |
Local angle | 59 ±1 | 58 ±1 | 58 ±1 | 58 ±1 | ns | ns | ns | ns | ns | ns | |
Local spline angle | 52 ±1 | 51 ±1 | 51 ±1 | 52 ±1 | ns | ns | ns | ns | ns | ns | |
Oblique# | 12.5 ±0.5 | 12.8 ±0.6 | 10.3 ±1.0 | 12.2 ±0.8 | ns | ns | ns | < 0.05 | ns | ns | |
Axon | Max horizontal extend (μm) | 1003 ±64 | 1035 ±69 | 639±55 | 1104 ±78 | ns | < 0.05 | ns | < 0.05 | ns | < 0.05 |
Max vertical extend (μm) | 1046 ±56 | 985 ±69 | 921 ±70 | 1107 ±61 | ns | ns | ns | ns | ns | < 0.05 | |
Length(μm) | 8704±604 | 9847 ±1154 | 5741±712 | 9079±923 | ns | < 0.05 | ns | < 0.05 | ns | < 0.05 | |
Surface(μm²) | 7680±1039 | 7898 ±800 | 3944±414 | 5360 ±887 | ns | < 0.05 | ns | < 0.05 | < 0.05 | ns | |
Volume(μm³) | 1348 ±473 | 1012±108 | 459 ±73 | 453 ±118 | ns | ns | ns | < 0.05 | < 0.05 | ns | |
Seg length (μm) | 107 ±4 | 95 ±4 | 106 ±6 | 125 ±5 | < 0.05 | ns | < 0.05 | ns | < 0.05 | < 0.05 | |
Seg surface (μm²) | 103 ±12 | 91 ±7 | 81 ±8 | 71 ±5 | ns | ns | < 0.05 | ns | < 0.05 | ns | |
Seg volume (μm³) | 19 ±6 | 14 ±2 | 11 ±2 | 6 ±1 | ns | ns | < 0.05 | ns | < 0.05 | < 0.05 | |
Seg# | 84 ±6 | 99 ±10 | 54 ±6 | 75 ±9 | ns | < 0.05 | ns | < 0.05 | ns | < 0.05 | |
Tortuosity | 1.21 ±0.01 | 1.17 ±0.01 | 1.20 ±0.01 | 1.20±0.01 | < 0.05 | ns | ns | < 0.05 | < 0.05 | ns | |
Max order | 12±0.5 | 12±0.5 | 10±0.5 | 12±0.7 | ns | < 0.05 | ns | < 0.05 | ns | < 0.05 | |
Max angles | 70 ±1 | 68 ±1 | 76 ±2 | 72 ±1 | ns | < 0.05 | ns | < 0.05 | < 0.05 | ns | |
Planar angle | 46 ±1 | 45 ±1 | 50 ±1 | 47 ±1 | ns | < 0.05 | ns | < 0.05 | < 0.05 | ns | |
Local angle | 60 ±1 | 58 ±1 | 61 ±1 | 58 ±1 | ns | ns | ns | ns | ns | ns | |
Local spline angle | 54 ±1 | 51 ±1 | 54 ±1 | 52 ±1 | < 0.05 | ns | ns | < 0.05 | ns | ns | |
Boton density (#/100 μm) | 15 ±1 | 16 ±1 | 21 ±1 | 21 ±1 | ns | < 0.05 | < 0.05 | < 0.05 | < 0.05 | ns |