Table 4.
Summary estimates of diagnostic test accuracy by field strategy, by index test grader, by pupil status and by setting
| Imaging strategy | Index grader | Non-mydriatic | Mydriatic | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | Sensitivity | Specificity | |||||||
| Estimate (95% CI) |
Number of studies | Estimate (95% CI) |
Number of studies | Estimate (95% CI) |
Number of studies | Estimate (95% CI) |
Number of studies | |||
| Overall estimates | 86% (85–87%) |
18 | 93% (92–93%) |
18 | 86% (85–87%) |
17 | 90% (89–90%) |
17 | ||
| By index test grader | Ophthalmologist | 82% (80–84%) |
7 | 94% (94–95%) |
7 | 87% (85–89%) |
9 | 93% (92–94%) |
9 | |
| Retinologist | 90% (89–92%) |
7 | 94% (93–95%) |
7 | 69% (62–75%) |
2 | 93% (91–96%) |
2 | ||
| Retinal reader | 89% (86–93%) |
3 | 91% (88–94%) |
3 | 86% (84–88%) |
4 | 92% (91–94%) |
4 | ||
| SpR registrar | 78% (75–81%) |
1 | 81% (79–82%) |
1 | 86% (84–89%) |
2 | 70% (68–72%) |
2 | ||
| By field strategy | 1F | Ophthalmologist | 73% (69–77%) |
3 | 96% (94–97%) |
3 | 78% (75–81%) |
4 | 94% (92–95%) |
4 |
| Retinologist | 79% (75–84%) |
3 | 81% (76–86%) |
3 | 69% (62–75%) |
2 | 93% (91–96%) |
2 | ||
| Retinal reader | 83% (77–87%) |
1 | 91% (88–94%) |
1 | 86% (81–89%) |
1 | 91% (88–93%) |
1 | ||
| SpR registrar | 78% (75–81%) |
1 | 81% (79–82%) |
1 | No data | – | No data | – | ||
| 2F | Ophthalmologist | 87% (84–90%) |
2 | 90% (88–92%) |
86% (83–89%) |
2 | 86% (84–88%) |
2 | ||
| Retinologist | 93% (91–95%) |
2 | 96% (94–97%) |
2 | No data | No data | ||||
| Retinal reader | No data | – | No data | – | 82% (78–85%) |
2 | 95% (92–97%) |
2 | ||
| SpR registrar | No data | – | No data | – | 86% (84–89%) |
2 | 70% (68–72%) |
2 | ||
| > 2F | Ophthalmologist | 84% (79–88%) |
2 | 97% (95–98%) | 2 | 93% (91–96%) |
3 | 96% (94–98%) |
2 | |
| Retinologist | 82% (75–90%) |
2 | 86% (8–90%) | 2 | No data | – | No data | – | ||
| Retinal reader | 93% (89–96%) |
2 | No data | – | 90% (86–93%) |
1 | 90% (87–92%) |
1 | ||
| SpR registrar | No data | – | No data | – | No data | – | No data | – | ||
| By setting | Primary | 85% (83–86%) |
8 | 92% (91–92%) | 8 | 82% (80–84%) |
6 | 91% (90–92%) |
6 | |
| Other (secondary or tertiary) | 90% (88–91%) |
10 | 95% (94–96%) | 10 | 87% (86–89%) |
11 | 89% (88–90%) |
11 | ||