Table 3.

Univariable and multivariable Cox regression analyses for regional lymph node recurrence

Characteristic	Neck		Upper mediastinum				Abdomen
	Univariable		Univariable		Multivariable		Univariable		Multivariable
	HR	95%CI	HR	95%CI	exp(B)	95%CI	HR	95%CI	exp(B)	95%CI
Age (≥ 60 v < 60)	0.64	0.26–1.55	1.02	0.47–2.23	–	–	0.47	0.21–1.06	–	–
Sex (male v female)	2.48	0.75–7.98	0.56	0.15–2.16	–	–	2.10	0.69–6.43	–	–
T stage (T1–2 v T3–4)	0.45	0.18–1.17	0.68	0.29–1.60	–	–	2.92	0.94–9.11	–	–
N stage (N0 v N1–3)	2.80	0.89–8.82	1.42	0.61–3.31	–	–	2.11	0.83–5.36	–	–
TNM stage (II v III + IV)	2.52	0.92–6.86	1.01	0.49–2.33	–	–	2.87	1.76–7.01	–	–
Length (≥ 4 cm v < 4 cm)	1.10	0.44–2.75	0.93	0.43–2.04	–	–	0.84	0.38–1.89	–	–
Tumour emboli (yes v no)	0.76	0.16–3.68	1.60	0.49–5.26	–	–	1.30	0.37–4.55	–	–
CT (yes v no)	1.27	0.52–3.12	1.20	0.56–2.60	–	–	1.25	0.56–2.77	–	–
RT (yes v no)	0.69	0.28–1.68	0.32	0.15–0.71	0.30	0.13–0.68	0.36	0.16–0.83	0.37	0.16–0.85
Positive LN in
UM (yes v no)	1.17	0.35–3.92	3.33	1.23–9.06	3.72	1.30–10.67	0.73	0.22–2.37	–	–
LM (yes v no)	2.97	1.19–7.39	1.24	0.56–2.71	–	–	0.67	0.29–1.57	–	–
Abdomen (yes v no)	0.92	0.37–2.66	1.00	0.46–2.16	–	–	2.59	1.15–5.85	2.57	1.12–5.92

CT chemotherapy, RT radiotherapy, LN lymph node, UM upper mediastinum, LM lower mediastinum

There were statistically significant differences for data in Italics (p < 0.05)