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. 2018 Nov 8;5(5):ENEURO.0171-18.2018. doi: 10.1523/ENEURO.0171-18.2018

Figure 2.

Figure 2.

Blocking action potentials does not affect GABAergic PSC frequency or amplitude in diestrous or proestrous mice. A, Representative recordings from a representative neuron in each group before (control or con, top) and during (bottom) TTX treatment (from n = 6 cells diestrous PM, n = 5 cells proestrous PM). B, Individual values and mean ± SEM of GABAergic PSC frequency. C, Average of all PSC traces for control or ttx periods from all cells in each group. D, E, Individual values and mean ± SEM for: (D) PSC amplitude, (E) decay time between 90% and 10% of the maximum current amplitude. No statistical differences were detected using two-way repeated-measures ANOVA/Bonferroni test (B, cycle stage: F(1,9) = 1.3; TTX: F(1,9) = 1.6; cycle stage × TTX: F(1,9) = 0.0; D, cycle stage: F(1,9) = 0.3; TTX: F(1,9) = 0.6; cycle stage × TTX: F(1,9) = 0.5; E, cycle stage: F(1,9) = 0.5; TTX: F(1,9) = 6.4 (p = 0.01); cycle stage × TTX: F(1,9) = 0.9).