Venn diagrams of the number of unique and shared differentially expressed genes in breast cell lines, after proton and electron irradiations. (A) MCF10A cell line deregulate 477 and 1483 genes after electron and proton irradiations, respectively. Moreover, a 81-gene signature of shared deregulate genes after both irradiation modalities, was also selected. (B) MCF7 BC cell line deregulate 2413 and 223 genes after electron and proton irradiations, respectively. Moreover, a 141-gene signature of shared deregulate genes after both irradiation modalities, was also selected. (C) MDA-MB-231 BC cell line deregulate 201 and 995 genes after electron and proton irradiations, respectively. Moreover, a 154-gene signature of shared deregulate genes after both irradiation modalities, was also selected.