Table 6.
oPOSSUM transcription factor binding sites analysis | |||||||
Particle | Deregulated genes (Down-Up) | TF | Downregulated genes | TF | Upregulated genes | TF | |
MCF10A/e- | e- | 558 | Sry; FoxD3; Sox5 | 179 | HoxA5; Sox5; Gfi | 379 | Sry;FoxD3;Sox5 |
p+ | 1564 | Egr1; Sp1; Klf4 | 943 | Egr1; Sp1; Klf4 | 621 | Sry;FoxI1;Arid3A | |
MCF7/e- | e- | 2554 | FoxI1; Arid3A; NFkB | 1272 | Arid3A; FoxD3; Sry | 1282 | Sp1;Mzf1;Klf4 |
p+ | 364 | FoxA1; Sry; FoxI1 | 68 | FoxA1; Mzf1; SpIB | 296 | FoxI1;FoxA1;Ap1 | |
MDA-MB-231/e- | e- | 355 | Arid3A; FoxD3; FoxI1 | 190 | Arid3A; FoxD3; FoxI1 | 165 | Sp1;Mzf1;Klf4 |
p+ | 1109 | ESR2; Pax4; Irf1 | 237 | Arid3A; TBP; Nkv2-5 | 872 | ESR2;Pax4;Myf |
TF, transcription factor.