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. 2018 Oct 10;8(10):180118. doi: 10.1098/rsob.180118

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© 2018 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 1. — Reduced miR-125a-5p is correlated with the poor prognosis of NSCLC. (a) miR-125a-5p levels in cancer tissues and adjacent normal tissues were determined by qPCR (n = 384). The middle line indicates median; bottom of box, 25th percentile; top of box, 75th percentile. *p < 0.05. (b) Kaplan–Meier survival curve of patients with high or low level of miR-125a-5p. (c) miR-125a-5p methylation levels in cancer tissues and adjacent normal tissues were determined (n = 384). The middle line indicates median; bottom of box, 25th percentile; top of box, 75th percentile. *p < 0.05. (d) Correlation between the mRNA level and the methylation level of miR-125a-5p.