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HPLC analysis of secondary metabolic profiles of the wild-type strain HB-J378 without or with (‘-la’) the supplementation of 2 mM LaCl3, and the in-frame deletion mutant of PKS genes. Peaks representing nocardiopsistin compounds were indicated by dashed lines. *, new peaks activated by LaCl3; ♦, nocardiopsistin C (3) is co-eluted at the same retention time with unknown compounds.
