Skip to main content
. 2018 Oct 21;9:175–191. doi: 10.1016/j.isci.2018.10.019

Figure 4.

Figure 4

Hepatic Function and Systemic Metabolism Are Improved in Fat-Transplanted aKO Mice

(A) Gross morphology of the liver (top panel) and liver sections stained with H&E (middle panel) and oil red O (bottom panel) at 16 weeks after surgery. Scale bars, 200 μm.

(B and C) Hepatic TG accumulation (B) and lipid metabolism-related gene expression (C) at 16 weeks after surgery.

(D and E) Hepatic glycogen (D) and gluconeogenesis-related gene expression (E) at 16 weeks after surgery.

(F–H) Plasma GOT and GPT activity (F), and hepatic inflammation- (G) and fibrosis- (H) related gene expression at 16 weeks after surgery.

(I–K) Locomotor activity (I), oxygen consumption (J), and RER (K) at 16 weeks after surgery.

(L) Plasma TG, FFA, cholesterol, and β-HB levels at 16 weeks after surgery.

Bars represent mean ± SE. (n = 6–8). Bars with different letters represent significant difference (p < 0.05) by one-way ANOVA with a post-hoc Tukey HSD test.