Table 3.
Univariate analysis examining relationship between individual factors of patients and severe RP
| Grade 0–1 RP | Grade 2–5 RP | p value | |
| Age | 72.7 ± 12.4 (n = 58) | 74.9 ± 10.8 (n = 10) | 0.599d |
| Sex (M:F) | 32:26 (n = 58) | 8:2 (n = 10) | 0.179e |
| SIa | 677.0 ± 842 (n = 54) | 592.5 ± 599.9 (n = 7) | 0.783d |
| KL-6b | 381.4 ± 317.9 (n = 44) | 438.9 ± 277.9 (n = 9) | 0615a |
| Tumour location (upper:middle or lower) | 37:21 (n = 58) | 3:7 (n = 10) | 0.085e |
| %VCc | 82.4 ± 20.0 (n = 30) | 84.0 ± 18.0 (n = 6) | 0.856a |
| FEV1%c | 68.3 ± 17.5 (n = 30) | 63.4 ± 16.6 (n = 6) | 0.517d |
| %FEV1c | 77.0 ± 28.2 (n = 30) | 69.4 ± 24.0 (n = 6) | 0.573d |
| COPD stagesc | 1.7 ± 0.9 (n = 30) | 1.8 ± 0.8 (n = 6) | 0.810d |
%FEV1, FEV1%/predicted FEV1%; %VC, vital capacity/predicted vital capacity; COPD, chronic obstructive pulmonary disease; FEV1%, percent of forced expiratory volume in 1 s; KL-6, serum Krebs von den Lungen-6; PTV, planning target volume; RP, radiation pneumonitis; SD, standard deviation; SI, smoking index.
Data are presented as mean ±SD or ratio.
a
SI, unknown in seven patients.
b
KL-6, unmeasured in 13 patients.
c
Respiratory function test, unexamined in 32 patients.
d
Analysis by the Mann–Whitney U test.
e
Analysis by the Fisher’s exact test.