Brain MRI of a 25-year-old female with Grade IV astrocytoma in the right frontal lobe The solid part of the tumor (the red arrow head) appears hypointense on T1WI (a) and hyperintense on T2WI (b) and T2FLAIR (c); the solid part of the tumor shows obvious heterogeneous enhancement on enhanced T1WI (d). The DWI (b = 1000 s mm–2) showed the solid part of the tumor as hyperintense (e); ADC value was 0.941 × 10−3 mm2 s–1 (f); the DWI [b = 1800 s mm–2 (g), b = 2500 s mm–2 (h), b = 3000 s mm–2 (i), b = 3500 s mm–2 (j), b = 4000 s mm–2 (k)] also showed the solid part of the tumor as hyperintense, the UHBV-ADC value was 0.160 × 10−3 mm2 s–1 (l). ADC, apparent diffusion coefficient; T1W1, T1 weighted image, T2W1, T2 weighted image; T2 FLAIR, T2 fluid-attenuated inversion recovery image; UHBV-ADC, ultrahigh-b-value-ADC.