Table 1.
Patient characteristics at onset of the childhood or young adulthood cancer (n = 121 patients)
| Characteristics | Patients n (%) |
| Year of the diagnosis of the first cancer | |
| <1980 | 62 (51.2) |
| 1981–1990 | 48 (29.7) |
| 1991–1995 | 11 (9.1) |
| Age at the diagnosis of the first cancer | |
| <1 year | 2 (1.7) |
| [1–5] years | 15 (12.4) |
| [5–10] years | 9 (7.4) |
| [10–15] years | 33 (27.3) |
| [15–20] years | 32 (26.4) |
| >20 years | 30 (24.8) |
| First cancer | |
| Hodgkin lymphoma | 76 (62.8) |
| Nephroblastoma | 17 (14.0) |
| Non-Hodgkin lymphoma | 7 (5.8) |
| Neuroblastoma | 3 (2.5) |
| Sarcoma | 8 (6.6) |
| Acute leukemia, lymphoblastic lymphoma | 4 (3.3) |
| Thyroid/oral and neck carcinoma | 2 (1.7) |
| Medulloblastoma | 1 (0.8) |
| Other | 3 (2.5) |
| Chemotherapy | |
| No | 20 (16.5) |
| Yes | 96 (79.3) |
| ND | 5 (4.1) |
| Surgery | |
| No | 83 (68.6) |
| Yes | 38 (31.4) |
| Pubertal stage at radiotherapy | |
| Pre-puberty | 26 (21.5) |
| Puberty | 20 (16.5) |
| Post-puberty | 75 (62.0) |
| Pregnancy in the 6 months before or after the radiotherapy | 3 (2.5) |
| Radiotherapy | |
| Field | |
| Supradiaphragmatic (mediastinal, pulmonary, +–- axillary area) | 99 (81.8) |
| Total body irradiation | 5 (4.1) |
| Abdominal | 16 (13.2) |
| Craniospinal | 1 (0.8) |
| Maximal estimated dose on the breast (Gy) where SBC was diagnosed | |
| <10 | 17 (14.0) |
| [10–20] | 19 (15.7) |
| >20 | 85 (70.2) |
Gy, Gray; ND, No data; SBC, second breast cancer.