Table 6.

Diagnostic performance for the detection of PZ prostate cancer with volume <0.5 ml stratified by presence of hemorrhage

	Reader 1			Reader 2
Present hemorrhage	Absent hemorrhage	p value	Present hemorrhage	Absent hemorrhage	p value
AUC	0.56 (0.44–0.68)	0.68 (0.58–0.77)	0.235	0.51 (0.39–0.63)	0.58 (0.48–0.68)	0.475
Sensitivity	0.33 (0.13–0.59) [6/18]	0.40 (0.19–0.64) [8/19]	0.663	0.06 (0.01–0.27) [1/18]	0.40 (0.19–0.64) [8/20]	0.016
Specificity	0.89 (0.78–0.96) [49/55]	0.85 (0.75–0.92) [69/81]	0.503	0.89 (0.78–0.96) [49/55]	0.79 (0.68–0.87) [63/80]	0.129
Positive predictive value	0.50 (0.27–0.73) [6/12]	0.40 (0.24–0.58) [8/20]	0.587	0.14 (0.02–0.56) [1/7]	0.32 (0.19–0.48) [8/25]	0.357
Negative predictive value	0.80 (0.74–0.85) [49/61]	0.85 (0.80–0.89) [69/80]	0.437	0.74 (0.71–0.77) [49/66]	0.84 (0.78–0.88) [63/75]	0.145

Data are 95% CI is in parentheses and numerators and denominators in brackets.