. Author manuscript; available in PMC: 2019 May 5.
Published in final edited form as: Nat Med. 2018 Nov 5;24(11):1743–1751. doi: 10.1038/s41591-018-0230-4
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms