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. 2018 Nov 2;10:5261–5271. doi: 10.2147/CMAR.S174066

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© 2018 Wu et al. This work is published and licensed by Dove Medical Press Limited

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The effect of radiation on HOTAIR expression in PC samples and cells.

Notes: (A) Volcano plots reporting the adjusted P-value and the log2 fold change of gene expression profile. Red points represented upregulated genes and green points represented downregulated genes. (B) HOTAIR expression was analyzed in 119 PC patients who received radiotherapy and 44 PC patients without radiotherapy. (C, D) HOTAIR expression was detected in PANC-1 and AsPC-1 cells every 2 hours after 0 or 4 Gy of radiation treatment. (E, F) HOTAIR expression was detected in PANC-1 and AsPC-1 cells after different doses (0, 2, 4, 6 Gy) of radiation treatment for 24 hours. *P<0.05.

Abbreviations: HOTAIR, HOX transcript antisense RNA; PC, pancreatic cancer.