Table 2.
Liver iron content, serum ferritin and hormonal parameters in patients with β-thalassemia major before and after Jadenu ® treatment.
| LIC | SF | TSH | FT4 | PTH | Vit.D | ||
|---|---|---|---|---|---|---|---|
| On Exjade ® | Mean | 29.47 | 2716.92 | 2.51 | 12.34 | 25.75 | 14.22 |
| n = 12 | SD | 16.01 | 2101.93 | 1.36 | 1.21 | 3.49 | 3.12 |
| On Jadenu ® | Mean | 26.66 | 2552.80 | 2.44 | 12.41 | 26.20 | 19.78 |
| n = 12 | SD | 13.48 | 1512.92 | 0.87 | 1.00 | 4.21 | 9.06 |
| P value | 0.31 | 0.36 | 0.41 | 0.40 | 0.13 | 0.09 |
Legend: LIC (mg/g/dry weight) = Liver iron concentration =; SF (ng/ml) = Serum ferritin; TSH (mIU/L) = thyrotropin; FT4 (pmol/L) = free T4; PTH (ng/mL) = serum parathormone; Vit. D (ng/mL) =25 OH vitamin D.