Table 3.
KIR GENES n (%) | cHBV | CONTROL | crude OR (95%CI) | crude P value |
---|---|---|---|---|
| ||||
Inhibitors | ||||
KIR2DL1 | ||||
| ||||
− | 30 (27.3) | 50 (37.3) | Ref. | |
| ||||
+ | 80 (72.7) | 84 (62.7) | 1.59 (0.92–2.74) | 0.097 |
| ||||
KIR2DL2 | ||||
| ||||
− | 63 (57.3) | 106 (79.1) | Ref. | |
| ||||
+ | 47 (42.7) | 28 (20.9) | 2.82 (1.61–4.96) | < 0.001 |
| ||||
KIR2DL3 | ||||
| ||||
− | 35 (31.8) | 72 (53.7) | Ref. | |
| ||||
+ | 75 (68.2) | 62 (46.3) | 2.49 (1.47–4.21) | < 0.001 |
| ||||
KIR2DL4 | ||||
| ||||
− | 33 (30.0) | 36 (26.9) | Ref. | |
| ||||
+ | 77 (70.0) | 98 (73.1) | 0.86 (0.49–1.5) | 0.589 |
| ||||
KIR2DL5A | ||||
| ||||
− | 70 (63.6) | 84 (62.7) | Ref. | |
| ||||
+ | 40 (36.4) | 50 (37.3) | 0.96 (0.57–1.62) | 0.878 |
| ||||
KIR2DL5B | ||||
| ||||
− | 61 (55.5) | 74 (55.2) | Ref. | |
| ||||
+ | 49 (45.5) | 60 (44.8) | 0.99 (0.60–1.64) | 0.971 |
| ||||
KIR3DL1 | ||||
| ||||
− | 36 (32.7) | 26 (19.4) | Ref. | |
| ||||
+ | 74 (67.3) | 108(80.6) | 0.49 (0.28–0.89) | 0.018 |
| ||||
KIR3DL2 | ||||
| ||||
− | 33 (30.0) | 20 (14.9) | Ref. | |
| ||||
+ | 77 (70.0) | 114(85.1) | 0.41 (0.22–0.77) | 0.005 |
| ||||
KIR3DL3 | ||||
| ||||
− | 29 (26.4) | 34 (25.4) | Ref. | |
| ||||
+ | 81 (73.6) | 100(74.6) | 0.95 (0.53–1.69) | 0.86 |
| ||||
Activators | ||||
KIR2DS1 | ||||
| ||||
− | 88 (80.0) | 88 (65.7) | Ref. | |
| ||||
+ | 22 (20.0) | 46 (34.3) | 0.48 (0.27–0.86) | 0.014 |
| ||||
KIR2DS2 | ||||
| ||||
− | 65 (59.1) | 114(85.1) | Ref. | |
| ||||
+ | 45 (40.9) | 20 (14.9) | 3.95 (2.15–7.25) | < 0.001 |
| ||||
KIR2DS3 | ||||
| ||||
− | 92 (83.6) | 110(82.1) | Ref. | |
| ||||
+ | 18 (16.4) | 24 (17.9) | 0.9 (0.46–1.75) | 0.75 |
| ||||
KIR2DS4 | ||||
| ||||
− | 43 (39.1) | 56 (41.8) | Ref. | |
| ||||
+ | 67 (60.9) | 78 (58.2) | 1.12 (0.67–1.87) | 0.669 |
| ||||
KIR2DS5 | ||||
| ||||
− | 66 (60.0) | 84 (62.7) | Ref. | |
| ||||
+ | 44 (40.0) | 50 (37.7) | 1.12 (0.67–1.88) | 0.668 |
| ||||
KIR3DS1 | ||||
| ||||
− | 98 (89.1) | 122(91.0) | Ref. | |
| ||||
+ | 12 (10.9) | 12 (9.0) | 1.24 (0.54–2.89) | 0.611 |
| ||||
Pseudogene | ||||
KIR2P1 | ||||
| ||||
− | 51 (46.4) | 40 (29.9) | Ref. | |
| ||||
+ | 59 (53.6) | 94 (70.1) | 0.49 (0.29–0.83) | 0.008 |