Table 5.
KIR GENES n (%) | VL< 2000 IU/mL | VL ≥ 2000 IU/mL | crude OR (95%CI) | crude P value |
---|---|---|---|---|
| ||||
Inhibitors | ||||
KIR2DL1 | ||||
| ||||
− | 17 (27.0) | 13 (27.7) | Ref. | |
| ||||
+ | 46 (73.0) | 34 (72.3) | 0.97 (0.41–2.26) | 0.937 |
| ||||
KIR2DL2 | ||||
| ||||
− | 37 (58.7) | 26 (55.3) | Ref. | |
| ||||
+ | 26 (41.3) | 21(44.7) | 1.15 (0.54–2.47) | 0.721 |
| ||||
KIR2DL3 | ||||
| ||||
− | 22 (34.9) | 13 (27.7) | Ref. | |
| ||||
+ | 41 (65.1) | 34 (72.3) | 1.4 (0.62–3.19) | 0.419 |
| ||||
KIR2DL4 | ||||
| ||||
− | 23(36.5) | 10(21.3) | Ref. | |
| ||||
+ | 40(63.4) | 37(78.7) | 2.13 (0.89–5.06) | 0.088 |
| ||||
KIR2DL5A | ||||
| ||||
− | 43(68.3) | 27 (57.4) | Ref. | |
| ||||
+ | 20(31.7) | 20 (42.6) | 1.59 (0.73–3.49) | 0.245 |
| ||||
KIR2DL5B | ||||
| ||||
− | 35(55.6) | 26(55.3) | Ref. | |
| ||||
+ | 28 (44.4) | 21(44.7) | 1.01 (0.47–2.16) | 0.98 |
| ||||
KIR3DL1 | ||||
| ||||
− | 22(34.9) | 14 (29.8) | Ref. | |
| ||||
+ | 41(65.1) | 33(70.2) | 1.26 (0.56–2.85) | 0.571 |
| ||||
KIR3DL2 | ||||
| ||||
− | 25 (39.7) | 8 (17.0) | Ref. | |
| ||||
+ | 38(60.3) | 39(83.0) | 3.21 (1.29–7.99) | 0.012 |
| ||||
KIR3DL3 | ||||
| ||||
− | 21(33.3) | 8 (17.0) | Ref. | |
| ||||
+ | 42(66.7) | 39(89.0) | 2.44 (0.97–6.14) | 0.059 |
| ||||
Activators | ||||
KIR2DS1 | ||||
| ||||
− | 49 (77.8) | 39 (83.0) | Ref. | |
| ||||
+ | 14 (22.2) | 8 (17.0) | 0.72 (0.27–1.88) | 0.501 |
| ||||
KIR2DS2 | ||||
| ||||
− | 41 (65.1) | 24 (51.4) | Ref. | |
| ||||
+ | 22 (34.9) | 23 (48.9) | 1.79 (0.83–3.86) | 0.141 |
| ||||
KIR2DS3 | ||||
| ||||
− | 55 (87.3) | 37 (78.7) | Ref. | |
| ||||
+ | 8 (12.7) | 10 (21.3) | 1.86 (0.67–5.15) | 0.233 |
| ||||
KIR2DS4 | ||||
| ||||
− | 29 (46.0) | 14 (29.8) | Ref. | |
| ||||
+ | 34 (54.0) | 33 (70.2) | 2.01 (0.91–4.46) | 0.086 |
| ||||
KIR2DS5 | ||||
| ||||
− | 37(58.7) | 29 (61.7) | Ref. | |
| ||||
+ | 26(41.3) | 18(38.3) | 0.88 (0.41–1.91) | 0.753 |
| ||||
KIR3DS1 | ||||
| ||||
− | 56(88.9) | 42 (89.4) | Ref. | |
| ||||
+ | 7(11.1) | 5 (10.6) | 0.95 (0.28–3.21) | 0.937 |
| ||||
Pseudogene | ||||
KIR2P1 | ||||
| ||||
− | 32 (50.8) | 19 (40.4) | Ref. | |
| ||||
+ | 31(49.2) | 28(59.6) | 1.52 (0.71–3.27) | 0.282 |