Figure 6. S. Typhimurium intestinal luminal expansion does not depend on Type 3 Secretion System 1-mediated gut tissue invasion.
A) 129 mice and antibiotic-pretreated B6 mice were infected with S. Typhimurium. CFU/g cecal contents and tissue at 1 day p.i. Bars represent the median. B) Antibiotic pre-treated B6 (black) and 129 (gray) mice were infected with a 1:1 mixture of wild type (WT) and ΔorgA SL1344. Data represent 2 independent experiments with 5 animals in each group. Error bars represent the standard error of the mean. Significance was calculated using an unpaired two-tailed t-test; **: p<0.01, ***: p<0.001. Unless noted, conditions are not significant.