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. Author manuscript; available in PMC: 2019 Oct 4.
Published in final edited form as: Mol Cell. 2018 Sep 13;72(1):48–59.e4. doi: 10.1016/j.molcel.2018.08.009

Figure 4.

Figure 4.

Ramatroban docking results. (A) Thermostability of unliganded CRTH2 and CRTH2 bound to ramatroban, fevipiprant and CAY10471. Apparent melting temperatures, Tms, were calculated and are shown in the brackets. Data points are presented as the mean values +/− SEM, n=2. (B) Binding pose of ramatroban, shown as dark purple sticks, from docking. CAY10471 is shown as thin yellow sticks for comparison. The carboxylate group in ramatroban is circled. See also Figure S4C.