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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Regen Eng Transl Med. 2018 Apr 23;4(3):120–132. doi: 10.1007/s40883-018-0054-2

Fig. 1. Schematic illustration of engineered lymphatic and vascular structures.

Fig. 1

(A) Acrylic plates and glass coverslip were assembled and glass rods were fixed in the culture chamber. Then, collagen gel was added and placed in an incubator for 15 min. After extraction of glass rods, cell suspensions of vascular endothelial cells (VEC) and lymphatic endothelial cells (LEC) were injected into the microchannels. After 24 h of static culture, a peristaltic pump was connected to both vessels to maintain a perfusion culture for 7-10 day and lymphangiogenesis and angiogenesis were observed (B). (C) Characterizations of lymphangiogenesis (LA) and vascular angiogenesis (VA) in cornea injury and tumorigenesis.