Table 2.

Examples of tweets expressing adverse drug reactions, indications, beneficial effects, and other information. Unified medical language system concept codes are shown in the first column

UMLS concept code	Comment type	Comment
Pain	ADR	Humira is the worst pain I have ever felt—and I’ve felt some pretty bad pain in life
Pain	Unsure	@username can’t sleep in pain, reminds me of your super woman strength to cope with it! How did ur first Humira injection go babe?
Pain	Indication or ADR	I just gave myself my first Humira injection. Ouch! Any suggestions on reducing the pain and making it more tolerable?
Pain	Other drug	I had terrible joint pain with Remicade. I switched to Humira and have had no major side effects
Pain	Beneficial	I’d like to add, Humira is kicking RA’s ass! I’ve got energy! Pain & swelling down a lot! Haven’t taken ibuprofen in 2 days either :)
Fatigue	ADR	Humira made me perpetually fatigued and sick
Fatigue	Unsure	One of those days—wicked tired and I have to get going to make it to physical therapy today. Two days after each Humira shot is sucky
Fatigue	Other drug	I think I am still trying to get over the tiredness from Ibiza and Humira is due
Fatigue	Beneficial	I could swear that Humira is giving me so much energy

ADR adverse drug reaction, UMLS unified medical language system