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. 2018 Oct 8;34(11):497–506. doi: 10.1007/s40267-018-0560-9
Novel monoclonal antibody that directly addresses the excess FGF23 activity in patients with XLH
Increases serum phosphate levels to within the normal range in children and adults
Improves the severity of rickets and other XLH-related outcomes in children with XLH
Improves XLH-related symptoms in adults with XLH
Well tolerated, with most adverse events being manageable without intervention