Table 5.
Studies investigating sex-related quality of life in transgender people (n = 4)
| Authors (year) Country |
Number of Trans participants, mean age at assessment | Treatment status | Study design | Comparative groups, follow-up | Outcome measures | Results | Factors associated | Conclusions |
|---|---|---|---|---|---|---|---|---|
| Bartolucci et al. (2015) [34] Spain |
67 TW 36 TM DSM-IV-TR 31.46 yrs. TW 28.69 yrs. TM |
Pre-GAGS 100% CHT 40% (TW 46% TM 28%) Post-CRS 30% (TW 35% TM 19%) |
Single centre Clinical group Cross-sectional |
Normative data (No follow-up) |
WHOQOL-100 | sQoL TW: Poor/very poor 48% Good 23% Very good 20% TM: Poor/very poor 54% Good 27% Very good 28% |
+ sQoL: CHT Having a partner Less negative feelings |
Pre-GAGS about half of trans sample perceived sexual QoL as either poor or very poor compared to the control group |
| Castellano et al. (2015) [73] Italy |
46 TW 14 TM 32.7 yrs. TW 30.2 yrs. TM |
+ 2 years post-GAGS 100% CHT 100% |
Single centre Clinical group Cross-sectional |
60 matched cis control sample (No follow-up) |
WHOQOL-100 | sQoL TW = 65.85 TM = 54.21 |
+QoL: Lower LH |
Trans people reported levels of QoL similar to cis controls |
| Kuhn et al. (2009) [81] Switzerland |
52 TW 3 TM 51 yrs. Trans |
CHT 100% GAGS 100% |
Single centre Clinical group Cross-sectional |
20 healthy female medical staff, not matched (No follow-up) |
KHQ | KHQ = 27.31 | None studied | 15-years post-GAGS QoL is lower for trans people in domains of General health, Role, Physical and Personal limitation than the cis control group |
| Manieri et al. (2014) [74] Italy |
56 TW 27 TM 32.7 yrs. TW 30.2 yrs. TM |
T0 = initiation of CHT 100% T1 = 3 months post-CHT 100% T2 = 6 months post-CHT 100% T3 = 9 months post-CHT 100% T4 = 1 year post-CHT 100% |
Single centre Clinical group Prospective longitudinal |
Pre- vs. during CHT | WHOQOL-100 | T4 TW: sQoL = 50.25 TM: sQoL = 62.05 |
None studied | TW reported significant improvement in sexual and general QoL 1 year post-CHT |
BI Body Image, CHT Cross-sex Hormonal Treatment, Cis Cisgender, CRS Chest Reconstructive Surgery, GAGS Gender Confirming Genital Surgery, LH Luteinizing Hormone, sQoL Sexual QoL, SR Social Relationships, TM Transgender men, TW Transgender women