Table 2.
Mean IOP over time: all eyes and low- and high-IOP subgroups
| All eyes (n = 53) | Baseline IOP ≤ 23 mmHg (n = 28) | Baseline IOP > 23 mmHg (n = 25) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean IOP (mmHg) ± SEa | Mean difference (mmHg) | IOP change (%) | Mean IOP (mmHg) ± SE | Mean difference (mmHg) | IOP change (%) | Mean IOP (mmHg) ± SE | Mean difference (mmHg) | IOP change (%) | |
| Baseline (n = 53) | 23.5 (1.1) | – | – | 18.1 (0.7) | – | – | 29.5 (1.3) | – | – |
| Day 1 (n = 53) | 13.2 (0.7) | − 10.3 | − 43.8 | 13.6 (0.8) | − 4.5 | − 24.9 | 12.9 (1.3) | − 16.6 | − 56.3 |
| Week 1 (n = 51) | 15.5 (1.0) | − 8.0 | − 34.0 | 14.6 (1.0) | − 3.5 | − 19.3 | 16.4 (1.7) | − 13.1 | − 44.4 |
| Month 1 (n = 52) | 15.5 (0.8) | − 8.0 | − 34.0 | 14.1 (0.7) | − 4.0 | − 22.1 | 16.9 (1.5) | − 12.6 | − 42.7 |
| Month 3 (n = 43) | 16.5 (0.9) | − 7.0 | − 29.8 | 15.0 (0.9) | − 3.1 | − 17.1 | 17.9 (1.6) | − 11.6 | − 39.3 |
| Month 6 (n = 53) | 15.0 (0.6) | − 8.5 | − 36.2 | 14.3 (0.5) | − 3.8 | − 21.0 | 15.8 (1.1) | − 13.7 | − 46.4 |
aReported are least squares means and associated standard errors from a mixed model for repeated measure analysis. Per Bonferroni pairwise comparison, the difference from baseline in mean IOP is statistically significant at each follow-up visit (p < 0.001)