Table 5.
Sensitivity and specificity profile of CMV real-time PCR
| Overall | Corneal disease type | Uveitis type | ||||
|---|---|---|---|---|---|---|
| 95% CI | 95% CI | 95% CI | ||||
| Sensitivity | 89.4% | 76.6–95.6% | 91.7% | 70.9–98.0% | 84.2% | 59.7–95.1% |
| Specificity | 94.0% | 88.8–96.9% | 88.9% | 75.4–95.4% | 95.5% | 88.3–98.3% |
| Positive predictive value | 82.4% | 69.2–90.7% | 81.5% | 61.6–92.3% | 80.0% | 56.2–93.3% |
| Negative predictive value | 96.6% | 92.0–98.6% | 95.2% | 82.2–98.9% | 96.6% | 89.7–98.9% |
| False positive rate | 17.7% | 9.3–30.8% | 18.5% | 7.7–38.4% | 20.0% | 7.4–43.8% |
| False negative rate | 3.4% | 1.4–8.0% | 4.8% | 1.1–17.8% | 3.5% | 1.1–10.3% |