Table 2.
Immunohistochemical expression of COX-2 and bcl-2 in the epithelial component of OKCs with hazard risks for recurrence
Recurrent cysts (n = 12) | Non-recurrent cysts (n = 29) | P value (Fisher’s exact test) | Cox proportional hazard model | |||
---|---|---|---|---|---|---|
HR (95% CI) | P value | |||||
COX-2 | 0% positive cells | 1 (8.3%) | 3 (10.34%) | 0.776 | 1.00 | |
1–25% positive cells | 3 (25.0%) | 12 (41.3%) | 0.812 (0.084–7.817) | 0.857 | ||
26–50% positive cells | 4 (33.3%) | 8 (27.6%) | 1.406 (0.157–12.601) | 0.76 | ||
Over 50% positive cells | 4 (33.3%) | 6 (20.7%) | 1.726 (0.193–15.445) | 0.626 | ||
bcl-2 | 0% positive cells | 1 (8.3%) | 10 (34.5%) | 0.274 | 1.00 | |
1–25% positive cells | 9 (75.0%) | 13 (44.9%) | 5.396 (0.681–42.765) | 0.111 | ||
26–50% positive cells | 2 (16.7%) | 4 (13.8%) | 4.327 (0.392–47.775) | 0.232 | ||
Over 50% positive cells | 0 (0.0%) | 2 (6.9%) | NR |
NR, no recurrence; HR, hazard ratio; CI, confidence interval