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. 2018 Feb 27;22(9):3079–3089. doi: 10.1007/s00784-018-2398-x

Table 6.

Individuals’ serum interleukin 6 and 8 concentrations; median (lower/upper quartile)

Parameters Chronic periodontitis;
ChP (n = 25)
Aggressive periodontitis;
AgP (n = 17)
ChP/AgP
p
Interleukin 6 [pg/ml] Baseline 1.6 (1.3/2.3) 1.1 (0.9/1.8) 0.074
12 weeks 1.3 (0.9/2.7) 1.4 (0.9/1.8) 0.787
Change baseline to 12 weeks − 0.2 (− 0.4/0.3) 0.1 (− 0.1/0.4) 0.976
60 months 1.6 (1.4/1.8) 1.4 (1.2/1.8) 0.174
Change baseline to 60 months 0 (− 0.6/0.3) 0.3 (− 0.5/0.7) 0.205
Change 12 weeks to 60 months 0.2 (− 1.1/0.6) 0.1 (− 0.1/0.4) 0.768
Interleukin 8 [pg/ml] Baseline 19.0 (14.3/32.0) 19.0 (11.5/23.3) 0.329
12 weeks 28.0 (22.0/43.0) 19.0 (10.8/33.3) 0.023
Change baseline to 12 weeks 4.0 (− 2.8/14.5) 0.0 (− 10.0/16.0) 0.457
60 months 16.4 (12.3/20.8)c 16.0 (12.9/19.6) 0.547
Change baseline to 60 months − 1.6 (− 15.6/3.1) − 2.0 (− 6.6/4.1) 0.788
Change 12 weeks to 60 months − 9.4 (− 18.4/− 5.8) − 1.0 (− 13.4/4.8) 0.079

Significantly different to 12 weeks: c(p < 0.001)