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N-TAAP (left-hand panels) and tryptic peptide profiles (right hand panels) from transgenic mice inoculated with C-BSE from a single UK source. Samples (200–300 mg) were divided into two replicates prior to PK treatment and processed and analysed in parallel, then data were combined to create the profiles. M1, M2: Tg110; M3, M4: Tg1896. TEmax: M1 = 5.5, M2 = 4.2, M3 = 4.5, M4 = 5.8.
