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. 2018 Nov 8;13(11):e0206812. doi: 10.1371/journal.pone.0206812

Table 3. Association between different obesity phenotypes with the presence of low BMD and osteoporosis.

Variable Model a 1
OR (95% CI)
P
Value
Model a 2
OR (95% CI)
P
Value
Model a 3
OR (95% CI)
P
Value
Low BMD

BMI
Obese Reference - Reference - Reference -
Overweight 1.358 (0.889–2.704) 0.157 0.533 (0.318–0.895) 0.017 0.539 (0.321–0.905) 0.019
Normal weight 2.310 (1.566–3.408) <0.001 0.399 (0.203–0.785) 0.008 0.402 (0.204–0.791) 0.008
Underweight 5.064 (3.168–8.097) <0.001 0.530 (0.202–1.389) 0.196 0.533 (0.203–1.399) 0.201

PBF
Q4 Reference - Reference - Reference -
Q3 0.511 (0.395–0.661) <0.001 0.466 (0.342–0.636) <0.001 0.466 (0.342–0.636) <0.001
Q2 0.606 (0.473–0.775) <0.001 0.693 (0.490–0.980) 0.038 0.694 (0.490–0.982) 0.039
Q1 0.629 (0.493–0.803) <0.001 0.764 (0.500–1.168) 0.215 0.761 (0.498–1.163) 0.207
Osteoporosis

BMI
Obese Reference - Reference - Reference -
Overweight 2.132 (0.471–9.661) 0.326 0.441 (0.079–2.454) 0.350 0.450 (0.081–2.499) 0.361
Normal weight 3.427 (0.823–14.271) 0.091 0.126 (0.015–1.083) 0.059 0.124 (0.014–1.070) 0.058
Underweight 16.523 (3.782–72.182) <0.001 0.185 (0.012–2.915) 0.230 0.179 (0.011–2.823) 0.221

PBF
Q4 Reference - Reference - Reference -
Q3 0.561 (0.288–1.091) 0.088 0.555 (0.255–1.208) 0.138 0.562 (0.257–1.226) 0.148
Q2 0.433 (0.211–0.888) 0.022 0.623 (0.248–1.564) 0.313 0.623 (0.247–1.573) 0.317
Q1 0.709 (0.382–1.315) 0.275 1.109 (0.391–3.144) 0.846 1.122 (0.395–3.192) 0.829

a Adjusted covariates:

Model 1 = age

Model 2 = Model 1 + proteinuria, TC, UA, Cr, AST, albumin, hsCRP, TSH

Model 3 = Model 2 + history of smoking, drinking