Table 1. Characteristics of patients with VTE.
| # patient | Gender | Age at wAIHA diagnosis |
Hemolysis at VTE |
Type of wAIHA | Hb level at AIHA diagnosis (g/dL) | Hb level at VTE diagnosis (g/dL) | Time between diagnosis of wAHAI and VTE (weeks) | VTE | Risk factors of VTE | Padua score at wAIHA diagnosis | Padua score at VTE diagnosis | APL | In/out patient | Days of hospitalization / days after discharge from previous hospitalization at VTE occurrence | Cause of hospitalization | Symptoms of VTE | Thrombotic prophylaxis | Anticoagulant and duration |
Relapse of VTE |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 81 | + | Primary | 8,2 | 8,2 | 0 | PE | Obesity | 3 | 3 | ND | Out | D1 | Dyspnea = > PE diagnosis | Dyspnea | None | VKA, long-term | 0 |
| 2 | F | 69 | + | Primary | 7,4 | 7,4 | 0,5 | PE+DVT | 0 | 1 | 1 | 0 | Out | D1 | Anemia | Calf pain | None | VKA, 1 year | 0 |
| 3 | M | 63 | + | Primary | 4,9 | 5,7 | 1 | DVT | Obesity | 1 | 1 | 0 | In | D2 | Anemia | None (systematic screening) | None | Rivaroxaban, 3 months | 0 |
| 4 | F | 54 | + | Primary | 5 | 4,8 | 3,5 | PE+DVT | Bed rest (due to anemia) |
5 | 8 | 0 | Out | D1 | Acute respiratory failure = > PE diagnosis | Dyspnea | None | VKA, 6 months | 0 |
| 5 | F | 42 | + | Primary | 8,9 | 6 | 4 | DVT | 0 | 0 | 0 | ND | In | D7 | Anemia | Lower limb edema | Prophylactic LMWH |
VKA, long-term | 2 |
| 6 | M | 76 | + | Secondary (low grade NHL) | 7,0 | 7 | 6 | DVT | 0 | 2 | 5 | 0 | Out | D1 / D28 discharge | Anemia | Lower limb edema | VKA (INR 1.5) |
VKA, long-term | 0 |
| 7 | M | 22 | - | Secondary (IIM) | 12,3 | 14 | 7 | PE+DVT | Bed rest + IVIg (2g/kg for IIM) | 3 | 3 | 0 | Out | D1 / D7 discharge | Chest pain = > PE diagnosis | Chest and calf pain | None | VKA, 6 months | 0 |
| 8 | F | 83 | + | Primary | 7,3 | 8,5 | 7 | PE+DVT | 0 | 0 | 0 | 0 | In | D7 | Anemia | Persisting dyspnea | None (referral from another hospital) |
VKA, 6 months | 0 |
| 9 | M | 32 | + | Primary | 5,4 | 9,2 | 7 | PE+DVT | IVIg (2g/kg for ITP) | 0 | 0 | 0 | Out | D1 / D15 discharge | Calf pain, dyspnea | Calf pain, dyspnea | None | VKA, 1 year | 0 |
| 10 | M | 86 | + | Secondary (low grade NHL) | 7,4 | 9,8 | 18 | DVT | 0 | 2 | 5 | 0 | In | D15 | Pancytopenia | Lower limb edema | None (thrombocytopenia <30 G/L) | VKA, 6 months | 0 |
| 11 | M | 54 | + | Secondary (HCV, cryoglobulinemia) |
5,6 | 6,6 | 23 | DVT | Nephrotic syndrome | 3 | 3 | 0 | Out | D1 / D7 discharge | Anemia | Calf pain | None | VKA, 6 months | 1 |
APL: antiphospholipid antibodies, DVT: deep vein thrombosis, F: female, Hb: hemoglobin, HCV: Hepatitis C Virus, IIM: Idiopathic Inflammatory Myopathy, IVIg: intravenous immunoglobulins, LMWH: Low Molecular Weight Heparin, M: male, ND: not determined, NHL: Non-Hodgkin Lymphoma, PE: pulmonary embolism, VKA: vitamin K antagonist, VTE: venous thromboembolism, wAIHA: warm autoimmune hemolytic anemia