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. 2018 Oct 29;14(10):e1007393. doi: 10.1371/journal.ppat.1007393

Fig 6. SmLeish impacts infection success by affecting the ability of haemocytes to encapsulate S. mansoni sporocysts.

Fig 6

Encapsulation of S. mansoni sporocysts was visualized using fluorescently labelled M-line haemocytes and incubating them with GFP (A) or SmLeish (B) knockdown sporocysts that had been transformed in vitro. GFP knockdown control sporocysts in which SmLeish expression remains intact were infrequently encapsulated (A and C) compared to SmLeish-knockdown sporocysts, which were more frequently encapsulated by 24 hours post incubation (p<0.0005) (B and C). Representative images of an encapsulated and non-encapsulated sporocyst at 12 and 24 hours post incubation are shown (A and B).