Figure 5. Change in the s6h5 loop conformation across the rate-limiting step.

Distribution of distances (left) from GDP’s β-phosphate to Ala331^G.s6h5.3 on the s6h5 loop before (blue) and after (orange) the rate-limiting step, as well as after GDP release (black). Representative structures of the s6h5 loop (right) are shown for before (top right, blue) and after (bottom right, orange) the rate limiting step.