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. 2018 Sep 29;13(8):808–821. doi: 10.1080/15592294.2018.1514232

Figure 4.

Figure 4.

Characteristic Kinefold structures of ± 50 nt next to the methylation site. Structures (A-E). ΔGl, open-sea sequences, G4-; A, C, D: methylation decrease by aging; B, E: methylation increase by aging. Structures (F-J). G4+, Ps- (according to Hotknots), ΔGh (> 18.14), methylation decrease by aging. The arrows indicate the epigenetic clock CpGs.