Table 3. Top ten SNPs from GWAS analysis of DNAm age predictions corresponding to peaks connected to LD blocks in HDMP (~2 Mbp). P-values were computed with a linear mixed-model (LMM).
SNP ID | Chr | Position |
LMM p-value |
Nearest gene(s) |
JAX00189882 | 6 | 77104479 | 1,08E-04 | Ctnna2, Lrrtm1 |
JAX00141186 | 6 | 55124351 | 1,59E-04 | Plekha8, Mturn, Znrf2, Nod1, Ggct, Gars, Crhr2, Inmt, Mindy4, Aqp1, Ghrhr, Adcyap1r1 |
JAX00613802 | 6 | 73641278 | 1,67E-04 | Dnah6, Suclg1, 4931417E11Rik |
JAX00651898 | 7 | 115070069 | 3,06E-04 | Calca, Calcb, Insc, Sox6 |
JAX00373522 | 14 | 14657081 | 4,48E-04 | Olfr720, Olfr31, Il3ra, Slc4a7, Nek10 |
JAX00049927 | 14 | 9498134 | 4,83E-04 | Fhit |
JAX00140799 | 6 | 49976398 | 5,06E-04 | Npy, Mpp6, Gsdme, Osbp13 |
JAX00189488 | 4 | 95990791 | 5,48E-04 | Fggy, Hook1, Cyp2j13, Cyp2j12, Cyp2j11, Cyp2j8 |
JAX00087970 | 19 | 25717022 | 5,66E-04 | Kank1, Dmrt1, Dmrt3, Dmrt2 |
JAX00374020 | 14 | 17587871 | 7,02E-04 | Thrb |