Table 1. King-specific gene list.
Gene symbol | Full gene name | Signal |
RFC3 | Replication factor C subunit 3 | DDR |
RFC4 | Replication factor C subunit 4 | DDR |
TOPBP1 | DNA topoisomerase 2-binding protein 1 | DDR |
ATR | Serine/threonine-protein kinase ATR | DDR |
ATM | Serine-protein kinase ATM | DDR |
CHK2 | Serine/threonine-protein kinase Chk2 | DDR |
ERCC1 | DNA excision repair protein ERCC-1 | NER |
BRCA1 | Breast cancer type 1 susceptibility protein | HR |
MCPH1 | Microcephalin | HR |
XRCC3 | X-ray repair cross-complementing protein 3 | HR |
CDK1 | Cyclin-dependent kinase 1 | HR |
HELQ | Helicase POLQ-like | HR |
RMI1 | RecQ-mediated genome instability protein 1 | HR |
GEN1 | Flap endonuclease GEN | HR |
SLX4 | Structure specific endonuclease subunit SLX4 | HR |
RAD54-like | DNA repair and recombination protein RAD54-like | HR |
APLF | Aprataxin and PNK-like factor | NHEJ |
SMARCAL1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 | NHEJ |
MLH1 | DNA mismatch repair protein Mlh1 | MMR |
MSH4 | MutS protein homolog 4 | MMR |
MGMT | Methylated-DNA—protein-cysteine methyltransferase | ADR |
DDR, DNA damage response; NER, nucleotide excision repair; HR, homologous recombination; NHEJ, non-homologous end-joining; MMR, mismatch repair; ADR, alkylation damage repair. The genes written in bold were used for quantitative PCR analysis in this study.