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Effects of Hydroyurea (HU) on RBC deformability measured at 290 mmosmol/l (DI 290). SCA without HU group: n = 91; SCA with HU group: n = 21; SCA with placebo group: n = 9; Control group: n = 113. Different from the SCA with HU group: **p < 0.01; ***p < 0.001. Different from the three SCA groups: ###p < 0.001.
