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. Author manuscript; available in PMC: 2019 Nov 7.
Published in final edited form as: Neuron. 2018 Sep 27;100(3):700–714.e9. doi: 10.1016/j.neuron.2018.08.043

Figure 8: PCP disrupted information coding of social salience and novelty by Direct-ON and Direct-OFF ensembles.

Figure 8:

(A) Top panels: schematic diagrams of the social behavior test performed in the absence of PCP. H, habituation; SB, sociability; SN, social novelty. E1 and E2 refer to empty containers; S1 and S2 refer to stranger1 and stranger 2, respectively. Middle and bottom panels: calcium activities of Direct-ON (middle panels) and Direct-OFF (bottom panels) ensembles responding to the two explorative targets at the H, SB and SN stages, n = 18 mice. (B) Top panels: schematic diagrams indicating the social behavior test under acute PCP influence. Middle and bottom panels: calcium activities of Direct-ON (middle) and Direct-OFF (bottom) ensembles responding to the two explorative targets at the H, SB and SN stages, n = 14 ~ 18 mice. Data were represented as mean ± SEM. See also Figure S8, Table S1.