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. 2018 Nov 2;5:296. doi: 10.3389/fmed.2018.00296

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Copyright © 2018 Witte, Zillikens and Schmidt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anti-laminin 332 BIOCHIP® mosaic. The mosaic contains HEK293 cells expressing the recombinant laminin 332 heterotrimer (Trim; upper left and middle left), the recombinant γ2- t β3-, and α3-chains of laminin 332 as well as negative control, cells transfected with the empty vector. Here, antibody binding is seen with the heterotrimer and the β3- and α3-chains in a patient with anti-laminin 332 mucous membrane pemphigoid.